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Gene amplification - definition of gene amplification by ...
The mere detection of EGFR protein expression or gene amplification on primary tumor cells has not been successful as a reliable predictor (2-4).

Amplification | Define Amplification at Dictionary.com
gene amplification An increase in the number of copies of a gene in a cell, resulting in an elevation in the level of the RNA or protein encoded for by the gene and a ...

HER2 Gene Amplification in Breast Cancer
HER2 Gene Amplification in Breast Cancer A Rogues’ Gallery of Challenging Diagnostic Cases: UKNEQAS Interpretation Guidelines and Research Recommendations

Notes on gene amplification - Columbia University
Notes on gene amplification Biol.G4054y ...

Clinical significance of TTF-1 protein expression and TTF ...
1. J Cell Mol Med. 2009 Aug;13(8B):1977-86. doi: 10.1111/j.1582-4934.2008.00594.x. Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in ...

Oncogene - Gene amplification of the histone ...
Figure 1. Determination of SETDB1 gene amplification and its association with RNA and protein overexpression in lung cancer cell lines. (a) Assessment of SETDB1 copy ...

Gene amplification of ribosomal protein S6 kinase-1 and -2 ...
1. Anticancer Res. 2013 Feb;33(2):469-75. Gene amplification of ribosomal protein S6 kinase-1 and -2 in gastric cancer. Yoshida S(1), Matsumoto K, Arao T, Taniguchi H ...

The RMM Blog - Rapid Microbiology and Rapid ...
Seattle–based, Stratos Genomics Inc, an innovator in molecular engineering and gene sequencing techniques, announced today the successful demonstration of nanopore ...

Modern Pathology - MET overexpression assessed by new ...
Modern Pathology features diagnostic anatomic pathology and contains original scientific papers, selected short courses, appropriate special lectures, reviews ...

MedTerms - Alpha Index, G listing - Medical Dictionary
Online Medical Dictionary and glossary with medical definitions, g listing.

 

 

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Yeast Cells Use Signaling Pathway to Modify Their Genomes
Genetic Engineering & Biotechnology News
Now scientists from the Babraham Institute and the University of Cambridge say that they have uncovered a likely mechanism, a signaling pathway that yeast cells can use to accomplish a specific kind of gene amplification, or gene duplication.


UC Berkeley

Engineers use light to turbocharge DNA diagnostics
UC Berkeley
Artist's rendering of photonic PCR on a chip using light to rapidly heat and cool electrons at the surface of a thin film of gold. This method yields gene amplification results in mere minutes, and promises to transform point-of-care diagnostics in ...

and more »


Performance characteristics of next-generation sequencing in clinical mutation ...
Nature.com
Next-generation sequencing was conducted using AmpliSeq Cancer Hotspot Panel (v2) for targeted multi-gene amplification, as described previously. Briefly, we used the Ion AmpliSeq Library Kit 2.0 for library preparation, Ion OneTouch 200 Template Kit ...


Genetic Engineering & Biotechnology News

PCR Shows Off Its Clinical Chops
Genetic Engineering & Biotechnology News
Clovis Oncology used a technology called BEAMing (Beads, Emulsions, Amplification, and Magnetics), a type of digital PCR for blood-based molecular testing, to perform EGFR testing on almost 250 patients in clinical trials. In BEAMing, individual EGFR ...


The cyanobacterium Mastigocladus fulfills the nitrogen demand of a terrestrial ...
Nature.com
The DNA was also used as a template for amplification of the nifH genes using the diazotrophic cyanobacteria-specific primers CN Forward (CNF) with a GC clamp and CN Reverse (CNR) (Olson et al., 1998) to generate amplicons 350 nucleotides in length.

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NAB2–STAT6 fusion types account for clinicopathological variations in solitary ...
Nature.com
However, Doyle et al have notified that STAT6 nuclear expression is driven by gene amplification and coamplified with CDK4 and MDM2 in a minor subset of dedifferentiated liposarcomas, a treacherous caveat liable to result in misdiagnosis of solitary ...


RB-loss puts focus on Myc
Nature.com
Indeed, chromatin immunoprecipitation (ChIP) experiments that examined the genome-wide distribution of E2F1, E2F4 and proteins involved in the Myc network described a very close association between E2F and Myc binding sites and their target genes ...

 

 

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